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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Last updated 14 September 2023

On 14 March 2023, the UK Medicines regulator approved an application to reclassify the erectile dysfunction medication Cialis. When marketed asCialis Together(tadalafil 10mg), it will be a ‘P’ (pharmacy) medication, and so available ‘over the counter’ in pharmacies – see. This follows the 2018, ‘P’ classification of (sildenafil 50mg) which has been available OTC, without a prescription, since then.

This decision is good news for men’s health …. Erectile dysfunction can be a debilitating condition, so it’s important men feel they have fast access to quality and legitimate care

Dr Laura Squire, MHRA’s Chief Officer for Healthcare, Quality and Access

Unfortunately, there is a strong black market in the UK for ED medicines, which are often unlicensed or counterfeit. UK Border Force and the MHRA seize millions of pounds of these fake products from criminals annually. This new classification of tadalafil 10mg will enable men who suffer from ED to obtain it safely from a local pharmacy.

Sanofi, the drug manufacturer, is expected to launch Cialis Together later in 2023. Cialis Together will be available to purchase in pharmacies without a prescription by men over 18 with erectile dysfunction. Cialis Together tablets will contain 10mg tadalafil and the maximum pack size will be 8 tablets. Other doses and pack sizes of Cialis and tadalafil will still be available on prescription through doctors and specially trained pharmacists. Before purchase in a pharmacy there must be an assessment with a pharmacist, who will check that Cialis Together is appropriate and safe, or whether consultation with a GP is necessary.

What does this mean for patients?

Men suffering with ED will have another treatment option with the convenience of purchasing it in their local pharmacy, including pharmacies found inside supermarkets (eg. Tesco, Asda, Sainsbury’s). The pharmacist will ask some health questions, may check blood pressure, and will advise on treatment with Cialis Together or Viagra Connect, or the need to consult a GP. Pharmacies usually have a private room for such discussions.

Cialis Together is a 10mg tadalafil product for use at least 30 minutes prior to anticipated sexual activity. Its effects can last. It is not recommended for daily use. The maximum recommended dose of Cialis Together will be one tablet in 24 hours. Prescription Cialis and tadalafil will still be available at different doses.

Dr Fox welcomes the wider access to ED medication for men that Cialis Together classified as a ‘P’ OTC medication will provide. We at Dr Fox are aware of the difficulties men have in discussing ED with their GPs and in accessing ED medication. We know that Cialis is effective and safe for most men and this change provides another option for obtaining ED treatment. Pharmacists are health professionals who are able to give ED advice but they will also know when to refer men who would benefit from a doctor’s assessment. ‘P’ medicines can also be supplied on prescription, and we will offer Cialis Together, when available, alongside our other competitively priced ED products.

Dr Claire Pugh, Dr Fox Medical Director

Categories of medicine

In the UK have 3 categories:

  • POM – Prescription only medicine:supplied by a healthcare professional following a consultation, usually on prescription.
  • P – Pharmacy medicine:supplied by a pharmacist ‘over the counter’, sometimes referred to as ‘P’ medicine or ‘PMED’.
  • GSL – General sales list medicine:available from many retail outlets ‘off the shelf’.
Read on and 10 in all this are 10 prescription only medicines used to treat erectile dysfunction and. These medicines are available aswenafil and sildenafil, both 100mg tablets, and aswenafil is. It is a ‘P’ medicine, which it is known as and is also used to treat erectile dysfunction ‘as needed’.
  • AND – Anti-SPF treatment medicine:available from many health-foods, supermarket chains, and online platforms ‘AND [for] [SPF]’.
  • Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

    Common side effects reported from Viagra use include:

    • Headache
    • Heartburn
    • Congestion
    • Nasal bleeding (bloody nose)
    • Nausea
    • Diarrhea
    • Muscle aches or pains
    • Flushing
    • Facial pain or tenderness
    • Vision changes
    • Light sensitivity

    More severe side effects include:

    • Painful erections or erections that last longer than 4 hours
    • Sudden loss of vision
    • Sudden loss of hearing
    • Ringing in the ears
    • Chest pain
    • Shortness of breath
    • Painful urination
    • Increased urination frequency
    • Fainting
    • Dizziness
    • Skin rash
    • Hives
    • Facial swelling

    If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

    As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.

    Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

    In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

    asthma in men (Alli)

    As with most medications, Viagra can cause potentially serious adverse reactions when taken with nitrates such as isosorbide dinitrate or nitroglycerine. The potentially cause of these reactions is unknown. If you take nitrates and experience any severe or life-threatening chest pain, contact your health care provider.

    angina

    Viagra can increase the risk of serious problems when taken with other medications such as blood pressure medications or certain antifungals. This is why it is important to tell your health care provider if you are taking Viagra.

    body ache (Vasotec)

    This side effect is not defined, but it is possible and reported. It is typically mild and non-persistent and does not require medical attention. If left untreated, it can cause a number of medical conditions, including dizziness, headache, weight gain, and flushing. As a result, potentially life-threatening reactions can occur.

    The chance is increased when taken with Viagra. Viagra can interact with certain medications, including certain drugs for high blood pressure, including amyl nitrate and nitrates. Specifically, Viagra can interact with isosorbide dinitrate or nitrates, along with medications for certain heart conditions. This combination can cause a dangerous rise in blood pressure.

    It is also possible to have allergic reactions to Viagra, like hives. Allergic reactions to medications can also occur, including rash, itching, swelling, and difficulty breathing. As a result, the need for medical attention is high.

    If you experience any side effects from taking Viagra, notify your doctor.

    flushing (Blokizer)

    Viagra can increase the risk of certain side effects when taken with medications containing nitrates such as isosorbide dinitrate or nitrates. The risk is increased when taken with Viagra.

    Viagra can interact with certain drugs, including certain nitrates, blood pressure medications, and certain antifungals.

    If you experience hives, difficulty breathing, or a rash, you should contact your doctor. As a result, immediate contact with your healthcare provider is recommended.

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    What Is The Best Medicines To Treat Men With ED?

    Men with certain health issues can benefit from the use of prescription medications.

    The most common medications that are prescribed for men with sexual problems include:

    Viagra is the brand name for the medication sildenafil, the active ingredient in Viagra.

    Cialis is another popular medication for men with ED.

    Levitra is a medication used to treat erectile dysfunction in men.

    Viagra is a popular drug for treating erectile dysfunction.

    Both medicines contain the same active ingredient, sildenafil, and work by increasing blood flow to the penis, making it easier to get and maintain an erection.

    What Are The Best Medications For Erectile Dysfunction?

    Men with erectile dysfunction can also benefit from the use of Viagra and Cialis.

    Both medications work by improving blood flow to the penis. In addition, Viagra and Cialis may help with erections in men who have difficulty getting or keeping an erection.

    While both drugs are effective, they differ in their side effects and how they affect your body.

    Cialis is the brand name for the medication tadalafil. It contains the same active ingredient as Viagra, which is used to treat erectile dysfunction in men.

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